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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FES
All Species:
20.61
Human Site:
S149
Identified Species:
45.33
UniProt:
P07332
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07332
NP_001996.1
822
93497
S149
Y
R
A
L
A
R
D
S
A
Q
A
K
R
K
Y
Chimpanzee
Pan troglodytes
XP_001169365
822
93450
S149
Y
R
A
L
A
R
D
S
A
Q
A
K
R
K
Y
Rhesus Macaque
Macaca mulatta
XP_001093848
823
93241
S149
Y
R
A
L
A
R
D
S
A
Q
A
K
R
K
Y
Dog
Lupus familis
XP_851836
820
93016
S147
Y
R
V
L
A
R
D
S
A
Q
A
R
R
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P16879
822
93760
S149
Y
R
T
L
V
R
D
S
T
Q
A
R
R
K
Y
Rat
Rattus norvegicus
P09760
323
37086
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512215
821
94492
V147
Y
R
Q
L
I
K
E
V
N
S
A
K
E
K
Y
Chicken
Gallus gallus
Q8JH64
657
75860
K82
P
E
R
Q
V
P
K
K
G
E
D
Y
N
M
E
Frog
Xenopus laevis
NP_001085865
822
94618
T153
Y
R
S
Q
V
K
E
T
F
Q
S
K
R
K
Y
Zebra Danio
Brachydanio rerio
XP_693576
842
96630
A148
Y
R
Q
L
T
K
D
A
V
L
A
R
E
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18106
1325
150245
A149
K
H
L
E
G
Y
K
A
L
R
T
R
F
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
94
N.A.
90.6
26.2
N.A.
51.9
24.7
64.5
50.2
N.A.
27.6
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.1
97.1
N.A.
95.2
32.5
N.A.
69.8
41.7
80.7
66.7
N.A.
41.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
0
N.A.
46.6
0
46.6
46.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
0
N.A.
60
6.6
80
66.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
0
37
0
0
19
37
0
64
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
55
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
19
0
0
10
0
0
19
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
28
19
10
0
0
0
46
0
73
0
% K
% Leu:
0
0
10
64
0
0
0
0
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
19
19
0
0
0
0
0
55
0
0
0
0
0
% Q
% Arg:
0
73
10
0
0
46
0
0
0
10
0
37
55
0
0
% R
% Ser:
0
0
10
0
0
0
0
46
0
10
10
0
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
10
10
0
10
0
0
0
0
% T
% Val:
0
0
10
0
28
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
73
0
0
0
0
10
0
0
0
0
0
10
0
0
73
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _